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HB 0028

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Drug Profile

HB 0028

Alternative Names: Anti-PD-L1 and TGF-β bifunctional fusion protein; HB-0028

Latest Information Update: 09 Jul 2024

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At a glance

  • Originator Huabo Biopharm
  • Class Antineoplastics; Recombinant fusion proteins
  • Mechanism of Action Programmed cell death-1 ligand-1 modulators; Transforming growth factor beta modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 31 May 2024 Efficacy and adverse events data from a phase-I/II clinical trials in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 09 Sep 2022 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in China (IV) (NCT06223308)
  • 05 Jul 2021 Preclinical trials in Solid tumours in China

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