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Nurandociguat - Bayer

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Drug Profile

Nurandociguat - Bayer

Alternative Names: BAY-3283142; sGC Activator 4 - Bayer

Latest Information Update: 04 Sep 2026

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At a glance

  • Originator Bayer
  • Class Alkanes; Antihypertensives; Biphenyl compounds; Carboxylic acids; Cardiovascular therapies; Chlorobenzenes; Fluorinated hydrocarbons; Hepatoprotectants; Piperazines; Piperidines; Pyrazoles; Small molecules; Urologics
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Renal failure
  • Phase I Cardiovascular disorders; Diabetic retinopathy; Hypertension; Liver disorders

Most Recent Events

  • 28 Jul 2026 Bayer initiates a phase I trial for Renal failure (In volunteers) in Germany (PO) (NCT07722585)
  • 12 May 2026 Bayer withdraws a phase I trial prior to enrolment in Renal failure in Germany as the study is no longer required (NCT07515339)
  • 15 Apr 2026 Chemical structure (structure, CAS number) information added.

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