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Tersolisib - Eli Lilly and Company

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Drug Profile

Tersolisib - Eli Lilly and Company

Alternative Names: LY-4064809; ST-814; STX-478; STX-H1047-PI3Ka inhibitors - Scorpion Therapeutics

Latest Information Update: 06 Feb 2026

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At a glance

  • Originator Scorpion Therapeutics
  • Developer Eli Lilly and Company; Scorpion Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Breast cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 14 Jan 2026 Eli Lilly and Company plans a phase I trial (In volunteers) (PO) in the USA (NCT07339735).
  • 12 Jan 2026 Eli Lilly and Company initiates enrolment in the phase I trial (In volunteers) in USA (PO) (NCT07339735)
  • 16 Dec 2025 Eli Lilly and Company completes phase I clinical trials in Solid tumours (In volunteers) in Singapore (PO) (NCT07247357)

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