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STX 478

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Drug Profile

STX 478

Alternative Names: ST-814; STX-478; STX-H1047-PI3Ka inhibitors - Scorpion Therapeutics

Latest Information Update: 23 Jun 2025

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At a glance

  • Originator Scorpion Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Colorectal cancer (CRC) presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 13 Jan 2025 Eli Lilly acquires STX 478 from Scorpion Therapeutics
  • 23 Dec 2024 Chemical structure information added.

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