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HLX 87

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Drug Profile

HLX 87

Alternative Names: GQ-1005; HLX-87

Latest Information Update: 29 Aug 2025

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At a glance

  • Originator Suzhou GeneQuantum Healthcare
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III HER2 positive breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 19 Aug 2025 HLX 87 licensed to Shanghai Henlius Biotech in China and certain overseas countries
  • 28 Feb 2025 HLX 87 approved to initiate a phase III trial for HER2-positive non-surgical resection/metastatic breast cancer
  • 28 Feb 2025 Suzhou GeneQuantum Healthcare plans to initiate a phase III trial for HER2-positive Breast cancer (Inoperable/Unresectable, Metastatic disease)

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