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HLX 87

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Drug Profile

HLX 87

Alternative Names: GQ-1005; HLX-87

Latest Information Update: 23 Dec 2025

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At a glance

  • Originator Suzhou GeneQuantum Healthcare
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III HER2 positive breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 23 Dec 2025 NMPA approves IND applications for HLX 22 in combination with HLX 87 in HER 2 positive breast cancer
  • 09 Dec 2025 Shanghai Henlius Biotech plans a phase II/III trial for HER2-positive-breast-cancer (Combination therapy, First-line therapy, Recurrent, Metastatic disease, Late-stage disease) (Injection) in January 2026 (NCT07294508)
  • 09 Dec 2025 Shanghai Henlius Biotech plans a phase II/III trial for HER2 positive breast cancer (Combination therapy, Neoadjuvant therapy, Late-stage disease, First-line therapy) in January 2026 (NCT07294534)

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