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AVB 101

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Drug Profile

AVB 101

Alternative Names: AVB-101; AVB-PGRN; AVB-PGRN (AVB-101)

Latest Information Update: 11 Oct 2024

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At a glance

  • Originator AviadoBio
  • Class Antidementias; Gene therapies
  • Mechanism of Action Gene transference; Progranulin protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Frontotemporal dementia
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Frontotemporal dementia

Most Recent Events

  • 08 Oct 2024 Astellas Pharma and AviadoBio enter into an exclusive option and license agreement for AVB 101
  • 28 Jul 2024 Pharmacodynamics data from a preclinical studies in frontotemporal dementia presented at the Alzheimers Association International Conference (AAIC-2024)
  • 06 Nov 2023 AVB 101 receives Fast track status from the US FDA for Frontotemporal dementia

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