Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

NC 525

Next Previous
Drug Profile

NC 525

Alternative Names: LAIR-1 mAb - NextCure; NC-525

Latest Information Update: 12 May 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator NextCure
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cell death stimulants; Leukocyte-associated immunoglobulin-like receptor 1 antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 24 Apr 2025 NextCure terminates a phase I trial in Myelodysplastic syndromes, Chronic myelomonocytic leukaemia and Acute myeloid leukaemia in USA as a result of program reprioritization and due to the limited clinical activity observed
  • 15 Nov 2023 Pharmacodynamics data from preclinical trial in Acute myeloid leukemia released by NextCure
  • 28 Feb 2023 Phase-I clinical trials in Chronic myelomonocytic leukaemia (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT05787496)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top