M 1069
Alternative Names: M-1069Latest Information Update: 28 Apr 2025
At a glance
- Originator Domain Therapeutics; Merck KGaA
- Developer EMD Serono Research & Development Institute; Merck KGaA
- Class Antineoplastics; Small molecules
- Mechanism of Action Adenosine A2A receptor antagonists; Adenosine A2B receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- No development reported Solid tumours
Most Recent Events
- 28 Apr 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Canada (PO, Capsule)
- 28 Apr 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO, Capsule)
- 10 Oct 2023 Serono terminates phase I trial on the basis of Overarching portfolio-level review of the company's oncology pipeline in Solid tumours (Metastatic disease, Late-stage disease, Inoperable/unresectable, Second-line therapy or greater) in USA and Canada (PO) (NCT05198349)