Drug Profile

HMGB 1

Alternative Names: HMGB-1

Latest Information Update: 28 Jan 2026

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At a glance

Originator 180 Life Sciences
Developer ETHZilla
Class Hepatoprotectants
Mechanism of Action Undefined mechanism

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Liver disorders

Most Recent Events

28 Jan 2026 No recent reports of development identified for preclinical development in Liver-disorders in United Kingdom
28 Jan 2026 No recent reports of development identified for preclinical development in Liver-disorders in USA
22 Sep 2022 180 Life Sciences terminates licensing agreement with Oxford University for HMGB 1

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