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Research programme: GABAB PAM - Addex Therapeutics

Drug Profile

Research programme: GABAB PAM - Addex Therapeutics

Alternative Names: GABAB PAM - Addex Therapeutics; GABAb receptor positive allosteric modulators (PAMs) - Addex Therapeutics

Latest Information Update: 17 Aug 2023

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At a glance

  • Originator Addex Therapeutics
  • Developer Addex Therapeutics; Charcot-Marie-Tooth Association
  • Class Small molecules
  • Mechanism of Action GABA B receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Charcot-Marie-Tooth disease; Cough; Interstitial cystitis; Pain; Substance-related disorders

Most Recent Events

  • 10 Aug 2023 Addex Therapeutics plans to initiate IND enabling studies for Cough in first half of 2024 (Addex Therapeutics pipeline, August 2023)
  • 10 Aug 2023 Addex Therapeutics plans to initiate IND enabling studies in substance related disorders in 2024 (Addex Therapeutics pipeline, August 2023)
  • 29 May 2023 Preclinical trials in Cough in Switzerland (unspecified route) (Addex Therapeutics pipeline, May 2023)
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