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GDC 4198

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Drug Profile

GDC 4198

Alternative Names: GDC-4198; RGT-419B

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Regor Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 inhibitors; Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I HER2 negative breast cancer; Solid tumours

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for phase-I development in HER2-negative-breast-cancer(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (PO, Capsule)
  • 28 Apr 2025 No recent reports of development identified for phase-I development in HER2-negative-breast-cancer(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy) in USA (PO, Capsule)
  • 30 Sep 2024 Genentech acquires RGT 419B from Regor

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