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Salanersen - Biogen/Ionis Pharmaceuticals

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Drug Profile

Salanersen - Biogen/Ionis Pharmaceuticals

Alternative Names: BIIB-115; ION-306

Latest Information Update: 24 Mar 2026

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At a glance

  • Originator Ionis Pharmaceuticals
  • Developer Biogen; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action RNA interference; Survival of motor neuron 2 protein expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Spinal muscular atrophy

Most Recent Events

  • 11 Mar 2026 Efficacy, adverse event and pharmacodynamics data from a phase I trial in Spinal muscular atrophy released by Biogen
  • 11 Mar 2026 Biogen plans a phase III SOLAR trial for Spinal muscular atrophy (In adolescents, In adults) in unknown location (Intrathecal, Injection) in Q2 2026 (NCT07444476)
  • 03 Mar 2026 Biogen plans a phase III STELLAR-2 trial for Spinal muscular atrophy (Treatment experienced, In neonates, In infants) in unknown location (Intrathecal, Injection) in September 2026 (NCT07444450)

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