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Salanersen - Biogen/Ionis Pharmaceuticals

Drug Profile

Salanersen - Biogen/Ionis Pharmaceuticals

Alternative Names: BIIB-115; ION-306

Latest Information Update: 01 Jul 2025

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At a glance

  • Originator Ionis Pharmaceuticals
  • Developer Biogen; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action RNA interference; Survival of motor neuron 2 protein expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Spinal muscular atrophy

Most Recent Events

  • 25 Jun 2025 Efficacy data from a phase I trial in Spinal muscular atrophy released by Biogen
  • 25 Jun 2025 Interim efficacy and adverse events data from a phase I trial in Spinal muscular atrophy released by Biogen
  • 25 Jun 2025 Biogen plans registrational phase III trials in Spinal muscular atrophy (Treatment-experienced, Treatment-naive) (Intrathecal, Injection)

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