Salanersen - Biogen/Ionis Pharmaceuticals
Alternative Names: BIIB-115; ION-306Latest Information Update: 01 Jul 2025
At a glance
- Originator Ionis Pharmaceuticals
- Developer Biogen; Ionis Pharmaceuticals
- Class Antisense oligonucleotides
- Mechanism of Action RNA interference; Survival of motor neuron 2 protein expression stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Spinal muscular atrophy
Most Recent Events
- 25 Jun 2025 Efficacy data from a phase I trial in Spinal muscular atrophy released by Biogen
- 25 Jun 2025 Interim efficacy and adverse events data from a phase I trial in Spinal muscular atrophy released by Biogen
- 25 Jun 2025 Biogen plans registrational phase III trials in Spinal muscular atrophy (Treatment-experienced, Treatment-naive) (Intrathecal, Injection)