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ARO ENaC2

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Drug Profile

ARO ENaC2

Alternative Names: ARO-ENaC2

Latest Information Update: 28 Mar 2026

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At a glance

  • Originator Arrowhead Pharmaceuticals
  • Class Antifibrotics; Small interfering RNA
  • Mechanism of Action Epithelial sodium channel antagonists; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cystic fibrosis

Most Recent Events

  • 28 Mar 2026 No recent reports of development identified for preclinical development in Cystic-fibrosis in USA (Parenteral)
  • 11 Feb 2022 Preclinical trials in Cystic fibrosis in USA (Parenteral) (Arrowhead Therapeutics website, February 2022)
  • 30 Sep 2021 Arrowhead Pharmaceuticals has patent protection for TRiM™ platform

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