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LYL 314

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Drug Profile

LYL 314

Alternative Names: CD19-CD20 bi-specific CAR-T - ImmPACT Bio; CD19-CD20 bi-specific chimeric antigen receptor-T cell therapy - ImmPACT Bio; IMPT-314; LYL-314

Latest Information Update: 23 Jun 2025

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At a glance

  • Originator ImmPACT Bio
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Non-Hodgkin's lymphoma
  • Phase I Chronic lymphocytic leukaemia

Most Recent Events

  • 17 Jun 2025 Efficacy and adverse events data from phase I/II clinical trials in Non-Hodgkin's lymphoma released by Lyell Immunopharma
  • 09 Jun 2025 Lyell Immunopharma announces intention to launch LYL 134 for Lymphoma
  • 13 May 2025 Lyell Immunopharma plans a pivotal trial for B-cell Lymphoma (Second-line therapy or greater) (Parenteral) in mid-2025

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