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AB 101 - Arbutus Biopharma

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Drug Profile

AB 101 - Arbutus Biopharma

Alternative Names: AB-101 - Arbutus Biopharma

Latest Information Update: 06 May 2026

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At a glance

  • Originator Arbutus Biopharma
  • Class Antivirals; Small molecules
  • Mechanism of Action Programmed cell death-1 ligand-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Hepatitis B

Most Recent Events

  • 09 Feb 2026 Arbutus Biopharma completes a phase Ia/Ib trial in Hepatitis B in Hong Kong, Italy, Moldova, New Zealand, Romania, Singapore, Ukraine (PO) (NCT05960240)
  • 14 May 2025 Updated adverse events and pharmacodynamics data from a phase Ia/Ib trial in Hepatitis B released by Arbutus Biopharma
  • 07 May 2025 Adverse events, pharmacokinetics and pharmacodynamics data from a phase Ia/Ib trial in Hepatitis B presented at the European Association for the Study of the Liver Congress 2025 (EASL-2025)

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