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AB 161

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Drug Profile

AB 161

Alternative Names: AB-161

Latest Information Update: 19 Sep 2023

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At a glance

  • Originator Arbutus Biopharma
  • Class Antivirals; Small molecules
  • Mechanism of Action Viral RNA degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Hepatitis B

Most Recent Events

  • 11 Sep 2023 Discontinued - Phase-I for Hepatitis B (In volunteers) in USA (PO) due to a preclinical toxicology finding, not related to peripheral neuropathy
  • 27 Apr 2023 Pharmacokinetics and pharmacodynamics data from preclinical studies in Hepatitis B released by Arbutus Biopharma
  • 16 Mar 2023 Phase-I clinical trials in Hepatitis B (In Volunteers) in USA (PO)

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