Drug Profile

Compound 27

Latest Information Update: 28 Jan 2026

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At a glance

Originator Astex Pharmaceuticals
Class Antineoplastics; Small molecules
Mechanism of Action Mitogen-activated protein kinase 1 inhibitors; Mitogen-activated protein kinase 3 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Acute myeloid leukaemia

Most Recent Events

28 Jan 2026 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (PO)
11 Dec 2021 Pharmacodynamics and pharmacokinetics data from a preclinical study in Acute myeloid leukaemia presented at the 63^rd American society of Hematology Annual Meeting and Exposition (ASH-2021)
31 May 2018 Preclinical trials in Acute myeloid leukaemia in USA (PO), prior to May 2018

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