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Lutetium-177 zadavotide guraxetan

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Drug Profile

Lutetium-177 zadavotide guraxetan

Alternative Names: 177-Lu PSMA imaging and therapy; 177-Lutetium-PSMA-I&T - Curium; 177Lu-PSMA-I&T; 177LU-PSMA-I&T; Lu-177-PSMA-I&T; Lutetium (177Lu) zadavotide guraxetan; Lutetium-177 prostate specific membrane antigen I&T; Lutetium-177 PSMA I&T; Lutetium-177 PSMA imaging and therapy

Latest Information Update: 22 Jan 2026

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At a glance

  • Originator Curium Pharma
  • Class Antineoplastics; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Prostate cancer

Most Recent Events

  • 07 Jan 2026 Centre for Drug Evaluation accepts IND for 177Lu-PSMA-I&T for Prostate cancer (Metastatic disease, Hormone refractory) for review
  • 07 Jan 2026 Curium Pharma plans a phase III trial for Prostate cancer (Hormone refractory, Metastatic disease) in China
  • 08 Aug 2025 PDRadiopharma plans a clinical trial in Prostate cancer (Hormone refractory, Metastatic disease) in Japan(IV)

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