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SNDX 50469

Drug Profile

SNDX 50469

Alternative Names: SNDX-50469; VTP-50469

Latest Information Update: 16 Jan 2024

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At a glance

  • Originator Vitae Pharmaceuticals
  • Developer Syndax Pharmaceuticals
  • Class Antineoplastics; Benzamides; Cyclohexanes; Fluorobenzenes; Phenyl ethers; Pyrimidines; Small molecules; Spiro compounds
  • Mechanism of Action Menin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 09 Dec 2023 Pharmacodynamics data from preclinical studies in Acute myeloid leukaemia and Precursor cell lymphoblastic leukaemia-lymphoma presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 11 Oct 2023 Preclinical trials in Precursor cell lymphoblastic leukaemia-lymphoma in USA (PO) (prior to October 2023)
  • 11 Oct 2023 Pharmacodynamics data from a preclinical study in Precursor cell lymphoblastic leukaemia-lymphoma presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)
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