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Olgotrelvir - ACEA Therapeutics

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Drug Profile

Olgotrelvir - ACEA Therapeutics

Alternative Names: Auvin; Olgotrelvir sodium - ACEA Therapeutics; OVYDSO; OVYDSO - Sorrento Therapeutics; STI-1558

Latest Information Update: 19 Aug 2026

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At a glance

  • Originator ACEA Therapeutics
  • Class Amides; Amines; Antivirals; Hepatoprotectants; Indoles; Obesity therapies; Osteoporosis therapies; Pyrrolidines; Small molecules; Sulfonic acids
  • Mechanism of Action Cathepsin L inhibitors; Coronavirus 3C protease inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered COVID 2019 infections
  • Phase I Chronic obstructive pulmonary disease
  • Preclinical Fatty liver; Obesity; Osteoporosis

Most Recent Events

  • 19 Aug 2026 Phase-I clinical trials in Chronic obstructive pulmonary disease in China (PO) prior to August 2026 (Zhejiang ACEA Pharmaceutical pipeline, August 2026)
  • 19 Aug 2026 Preclinical trials in Osteoporosis in China (PO) prior to August 2026 (Zhejiang ACEA Pharmaceutical pipeline, August 2026)
  • 19 Aug 2026 Preclinical trials in Fatty liver in China (PO) prior to August 2026 (Zhejiang ACEA Pharmaceutical pipeline, August 2026)

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