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9MW 2821

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Drug Profile

9MW 2821

Alternative Names: 9MW-2821

Latest Information Update: 24 Feb 2025

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At a glance

  • Originator Mabwell (Shanghai) Bioscience
  • Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Oesophageal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Cervical cancer; Urogenital cancer
  • Phase II Triple negative breast cancer
  • Phase I/II Solid tumours
  • Phase I Bladder cancer

Most Recent Events

  • 21 Jan 2025 Phase-II clinical trials in Urogenital cancer (Combination therapy, First-line therapy, In adults, In the elderly, Late-stage disease, Metastatic disease) in China (IV) (NCT06823427)
  • 08 Jan 2025 9MW 2821 receives Breakthrough Therapy status for Urogenital cancer (First-line therapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable) in China
  • 08 Jan 2025 Efficacy data from a phase III trial in Urogenital cancer released by Mabwell Therapeutics

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