Drug Profile

Zoldonrasib - REVOLUTION Medicines

Alternative Names: RMC-9805

Latest Information Update: 06 May 2025

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At a glance

Originator REVOLUTION Medicines
Class Acetamides; Antineoplastics; Piperazines; Pyridazines; Pyridines; Small molecules
Mechanism of Action KRAS protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Non-small cell lung cancer

Most Recent Events

27 Apr 2025 Updated efficacy and adverse events data from a phase I/Ib trial in Solid tumours released by Revolution Medicines
26 Feb 2025 REVOLUTION Medicines plans the one or more pivotal combination trials of zoldonrasib in 2026
25 Oct 2024 Efficacy and adverse events data from a phase I/Ib trial in Solid tumours released by Revolution Medicines

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