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LOXO 260

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Drug Profile

LOXO 260

Alternative Names: LOX-19260; LOXO-260; LY-3838915

Latest Information Update: 04 Sep 2026

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At a glance

  • Originator Eli Lilly and Company; Loxo Oncology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-ret inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 03 Jun 2026 Eli Lilly and Company completes a phase-I trials in Solid tumours (In adolescents, In the elderly, Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater, In adults) in USA (PO) (NCT05241834)
  • 23 Oct 2024 Pharmacokinetic, adverse events and efficacy data from a phase I trial in Solid tumors presented at the 36th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics (EORTC-NCI-AACR-2024)
  • 12 May 2022 Phase-I clinical trials in Solid tumours (In adolescents, In the elderly, Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater, In adults) in USA (PO) (NCT05241834)

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