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SAR 442970

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Drug Profile

SAR 442970

Alternative Names: Anti-TNFa and OX40L - Sanofi; Anti-TNFa/OX40L - Sanofi; NANOBODY®; SAR-442970; VHH antibody

Latest Information Update: 25 Oct 2024

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At a glance

  • Originator Sanofi
  • Class Anti-inflammatories; Monoclonal antibodies; Single-domain antibodies; Skin disorder therapies
  • Mechanism of Action OX40 ligand inhibitors; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Focal segmental glomerulosclerosis; Hidradenitis suppurativa
  • Phase I Inflammation

Most Recent Events

  • 22 Aug 2024 Phase-II clinical trials in Focal segmental glomerulosclerosis (In adolescents, In adults, In the elderly) in USA (Parenteral) (NCT06500702)
  • 15 Jul 2024 Sanofi plans the phase IIa RESULT trial for Focal segmental glomerulosclerosis (In adolescents, In adults, In the elderly) in September 2024 (NCT06500702)
  • 15 Jun 2023 Phase-II clinical trials in Hidradenitis suppurativa (In adults, In the elderly) in Canada (Parenteral) (NCT05849922) (EudraCT2022-502370-17-00)

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