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AGA 2118

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Drug Profile

AGA 2118

Alternative Names: AGA-04; AGA-2118

Latest Information Update: 02 Feb 2026

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At a glance

  • Originator Angitia
  • Class Bispecific antibodies; Osteoporosis therapies
  • Mechanism of Action DKK1 protein inhibitors; SOST protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Osteoporosis

Most Recent Events

  • 05 Jan 2026 Angitia Incorporated Limited initiates a phase I pharmacokinetics trial (In volunteers) in US (NCT07361354)
  • 05 Jan 2026 Angitia Biopharmaceuticals completes enrolment in its phase II ARTEMIS trial for Osteoporosis (In Adults, In the elderly) in the US, Poland, Ukraine and Argentina (SC) (NCT06577935)
  • 14 Sep 2025 Pharmacodynamic and pharmacokinetic data from a phase I trial in Osteoporosis presented at the 2025 American College of Clinical Pharmacology Annual Meeting (ACCP-2025)

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