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ASP 2138

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Drug Profile

ASP 2138

Alternative Names: ASP-2138

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Astellas Pharma; Xencor
  • Developer Astellas Pharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Gastric cancer; Oesophageal cancer; Pancreatic cancer

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Gastric-cancer(In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, In adults) in Japan (IV, Infusion)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Oesophageal-cancer(In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, In adults) in Japan (IV, Infusion)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Pancreatic-cancer(In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, In adults) in Japan (IV, Infusion)

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