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RO 7308480

Drug Profile

RO 7308480

Alternative Names: NTX-1955; RO-7308480

Latest Information Update: 25 Sep 2025

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At a glance

  • Originator Roche
  • Developer Newleos Therapeutics; Roche
  • Class Behavioural disorder therapies
  • Mechanism of Action GABA A receptor positive allosteric modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Anxiety disorders

Most Recent Events

  • 08 Aug 2025 Newleos Therapeutics initiates the phase I CO2 challenge trial (In volunteers) in the Netherlands (CTIS2025-522281-68-00)
  • 30 Jul 2025 Phase-I clinical trials in Anxiety disorders in European Union (PO)
  • 23 Jul 2025 Newleos Therapeutics files clinical trial applications (CTAs) with the competent health authorities for two phase Ib studies of NTX 1955 in EU for Anxiety disorders (PO) before July 2025

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