Drug Profile

NTX 1955

Alternative Names: NTX-1955; RO-7308480

Latest Information Update: 25 Sep 2025

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At a glance

Originator Roche
Developer Newleos Therapeutics; Roche
Class Anxiolytics; Behavioural disorder therapies
Mechanism of Action GABA A receptor positive allosteric modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Generalised anxiety disorder

Most Recent Events

08 Aug 2025 Newleos Therapeutics initiates the phase I CO2 challenge trial (In volunteers) in the Netherlands (CTIS2025-522281-68-00)
30 Jul 2025 Phase-I clinical trials in Generalised anxiety disorders in European Union (PO)
23 Jul 2025 Pharmacodynamics data from a preclinical trial in Generalized anxiety disorder released by Newleos Therapeutics

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