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Mefuraniper hydrochloride- Convalife

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Drug Profile

Mefuraniper hydrochloride- Convalife

Alternative Names: CVL-218; Mefuparib hydrochloride - Convalife

Latest Information Update: 23 Dec 2025

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At a glance

  • Originator Convalife
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Preclinical COVID 2019 infections; COVID-19 pneumonia

Most Recent Events

  • 23 Dec 2025 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Combination therapy) in China (PO), prior to December 2025 (Convalife pipeline, December 2025) (NCT06078670)
  • 10 Dec 2024 Efficacy and adverse events data from a phase I/II trial in Solid tumors presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024) .
  • 25 Feb 2022 Preclinical trials in COVID-19 pneumonia in China (unspecified route)

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