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INCB 123667

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Drug Profile

INCB 123667

Alternative Names: INCB-123667

Latest Information Update: 09 Sep 2025

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At a glance

  • Originator Incyte Corporation
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ovarian cancer
  • Phase I Solid tumours

Most Recent Events

  • 09 Sep 2025 Efficacy and adverse events data from phase-I trial in Solid presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 05 Sep 2025 INCB 123667 is still in phase I trial for Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in the US, France, Italy, Japan, the Netherlands, Puerto Rico, Switzerland, and the United Kingdom (PO, Tablet)
  • 28 Aug 2025 Phase-II clinical trials in Ovarian cancer (Second-line therapy or greater) in Puerto Rico (PO) (NCT07023627)

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