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M atrial natriuretic peptide

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Drug Profile

M atrial natriuretic peptide

Alternative Names: Frameshift ANP; Frameshift ANP - Mayo Clinic/E-Star Biotech; Frameshift atrial natriuretic peptide; fsANP; M-atrial natriuretic peptide; MANP; ZD-100

Latest Information Update: 28 Oct 2023

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At a glance

  • Originator Mayo Clinic
  • Developer E-Star BioTech; Mayo Clinic
  • Class Antihypertensives; Natriuretic peptides
  • Mechanism of Action Atrial natriuretic factor receptor A agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Essential hypertension
  • No development reported Resistant hypertension

Most Recent Events

  • 28 Oct 2023 No recent reports of development identified for phase-I development in Resistant-hypertension(In the elderly, In adults) in USA (SC, Injection)
  • 31 Oct 2022 E-Star Biotech in collaboration with Mayo Clinic completes a phase Ib trial in Difficult to control hypertension and Resistant hypertension in USA (NCT05247528)
  • 23 Feb 2022 E-Star Biotech in collaboration with Mayo Clinic initiates phase I trial in Resistant hypertension (In adults, In the elderly) in USA (SC) (NCT05247528)

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