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TT 01488

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Drug Profile

TT 01488

Alternative Names: TT-01488

Latest Information Update: 25 Feb 2026

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At a glance

  • Originator TransThera Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I B-cell lymphoma; Chronic lymphocytic leukaemia; Mantle-cell lymphoma; Waldenstrom's macroglobulinaemia

Most Recent Events

  • 25 Feb 2026 Phase-I development in Waldenstrom's macroglobulinaemia, Chronic-lymphocytic-leukaemia, Mantle-cell-lymphoma (Second-line therapy or greater) in USA (PO, Tablet) (TransThera Biosciences pipeline, February 2026)
  • 06 Dec 2025 Efficacy, pharmacokinetics and adverse events data from a phase I trial in B-cell-lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 28 Jul 2025 No recent reports of development identified for phase-I development in Chronic-lymphocytic-leukaemia(Second-line therapy or greater) in USA (PO, Tablet)

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