Drug Profile

AG 181

Alternative Names: AG-181; PAH - Agios Pharmaceuticals

Latest Information Update: 25 Feb 2025

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At a glance

Originator Agios Pharmaceuticals
Class Small molecules
Mechanism of Action Phenylalanine hydroxylase modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I Phenylketonuria

Most Recent Events

01 Feb 2025 AGIOS Pharmaceutical has patent protection for AG-181 in USA
31 Dec 2024 AGIOS Phamaceuticals issues patents and pending patent applications in Argentina, Australia, Brazil, Canada, China, Europe, Japan, Lebanon, Mexico, Eurasia, Saudi Arabia, and Taiwan
20 Feb 2024 Phase-I clinical trials in Phenylketonuria (In volunteers) in USA (PO) (NCT06286033)

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