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MR 1 114

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Drug Profile

MR 1 114

Alternative Names: coronavirus papain-like protease inhibitors - Sunshine Biopharma/University of Arizona/University of Illinois Chicago; MR1-114; PLpro inhibitors-Sunshine Biopharma/University of Arizona

Latest Information Update: 25 Aug 2026

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At a glance

  • Originator University of Arizona; University of Illinois at Chicago
  • Developer Sunshine Biopharma; University of Arizona; University of Illinois at Chicago
  • Class Antivirals; Small molecules
  • Mechanism of Action SARS-CoV-2 papain-like protease inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical COVID 2019 infections

Most Recent Events

  • 20 Jul 2026 Preclinical trials in COVID-2019 infections in USA prior to July 2026 (unspecified route)
  • 20 Jul 2026 Pharmacodynamics and pharmacokinetics data from a preclinical trial in COVID-2019 infections released by Sunshine Biopharma
  • 29 May 2026 Sunshine Biopharma has patent protection for Compounds and Methods for Treatment of Coronavirus Infection in USA

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