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AEV 103

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Drug Profile

AEV 103

Alternative Names: 3,6’-dithiopomalidomide; 3,6’-DP; AEV-103

Latest Information Update: 28 Apr 2026

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At a glance

  • Originator National Institutes of Health (USA)
  • Developer AevisBio; National Institute on Aging; National Institutes of Health (USA); Yonsei University
  • Class Imides; Small molecules
  • Mechanism of Action Immunomodulators; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Alzheimer's disease; Brain injuries

Most Recent Events

  • 28 Apr 2026 No recent reports of development identified for preclinical development in Alzheimer's-disease in South Korea
  • 28 Apr 2026 No recent reports of development identified for preclinical development in Brain injuries in South Korea
  • 12 Apr 2022 AEV 103 is under IND-enabling studies in South Korea (AevisBio pipeline, April 2022)

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