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AGLE 325

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Drug Profile

AGLE 325

Alternative Names: AGLE-325

Latest Information Update: 26 Dec 2023

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At a glance

  • Originator Aeglea Biotherapeutics
  • Developer Spyre Therapeutics
  • Class Enzymes; Recombinant proteins; Urologics
  • Mechanism of Action Enzyme replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Cystinuria

Most Recent Events

  • 08 Mar 2023 Discontinued - Preclinical for Cystinuria in USA (unspecified route)
  • 14 Mar 2022 Pharmacodynamics data from preclinical studies in Cystinuria presented by Aeglea Biotherapeutics
  • 10 Mar 2022 AGLE 325 is available for licensing as of 10 Mar 2022. https://www.aeglea.com/partnering/

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