Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

KRM II 81

Next Previous
Drug Profile

KRM II 81

Alternative Names: KRM-II-81

Latest Information Update: 27 Nov 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator University of Wisconsin at Milwaukee
  • Developer RespireRx Pharmaceuticals; University of Wisconsin at Milwaukee
  • Class Analgesics; Antiepileptic drugs; Anxiolytics; Small molecules
  • Mechanism of Action GABA A receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Epilepsy; Pain

Most Recent Events

  • 19 Nov 2025 The UWM Research Foundation (UWMRF) and RespireRx Pharmaceuticals have amended and restated their patent license agreement
  • 23 Sep 2025 RespireRx Pharmaceuticals receives SBIR grant from National Institutes of Health (NIH) and National Institute of Neurological Disorders and Stroke (NINDS) for KRM II 81 development in Epilepsy
  • 05 Dec 2022 RespireRx Pharmaceuticals enters a collaboration with National Institute of Neurological Disorders and Stroke to develop KRM II 81 in Pain

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top