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Fluorine-18 FAPI 74

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Drug Profile

Fluorine-18 FAPI 74

Alternative Names: [18F]FAPI-74

Latest Information Update: 10 Sep 2025

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At a glance

  • Originator University of Heidelberg
  • Developer SOFIE
  • Class Fluorine radioisotopes; Imaging agents; Quinolines; Radioisotopes; Radiopharmaceutical diagnostics
  • Mechanism of Action Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Fever of unknown origin
  • Phase II Gastrointestinal cancer
  • Phase I Solid tumours

Most Recent Events

  • 27 Aug 2025 Phase-II/III clinical trials in Fever of unknown origin (Diagnosis) in Belgium (IV) (CTIS2024-516464-28-00)
  • 19 Jun 2025 GE Healthcare in collaboration with Leiden University Medical Center plans a phase II/III PLASTIC-3 trial in Adenocarcinoma (Diagnosis) in Netherlands (IV) in June 2025 (NCT07018661)
  • 15 Jan 2025 18-F FAPI 74 is available for licensing as of 15 Jan 2025. www.sofie.com

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