Drug Profile

Research programme: mesothelin targeted trispecific killer engager - GT Biopharma

Alternative Names: Mesothelin targeted TriKE - GT Biopharma; MSLN-targeted TriKE - GT Biopharma

Latest Information Update: 28 Apr 2026

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At a glance

Originator GT Biopharma
Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Interleukins; Recombinant fusion proteins
Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin 15 replacements; Natural killer cell stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Apr 2026 No recent reports of development identified for preclinical development in Non-small-cell-lung-cancer in USA (Parenteral)
09 Mar 2022 Preclinical trials in Non-small cell lung cancer in USA (Parenteral)
09 Mar 2022 Pharmacodynamics data from a preclinical trial in Non-small cell lung cancer released by GT Biopharma

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