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Aleniglipron - Gasherbrum Bio

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Drug Profile

Aleniglipron - Gasherbrum Bio

Alternative Names: GSBR-1290

Latest Information Update: 12 Dec 2025

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At a glance

  • Originator Gasherbrum Bio
  • Developer Gasherbrum Bio; Structure Therapeutics
  • Class Antihyperglycaemics; Antiparkinsonians; Obesity therapies; Small molecules
  • Mechanism of Action Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Obesity; Type 2 diabetes mellitus
  • Preclinical Parkinson's disease

Most Recent Events

  • 09 Dec 2025 Topline adverse events and efficacy data from a phase IIb ACCESS trial and OLE ACCESS trial in Obesity released by Structure Therapeutics
  • 08 Dec 2025 Structure Therapeutics plans to request a Type B End-of-Phase 2 meeting with the United States Food and Drug Administration (FDA) in the first half of 2026.
  • 08 Dec 2025 Interim adverse events data from a phase IIb body composition study in Obesity released by Structure Therapeutics

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