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Aleniglipron - Gasherbrum Bio

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Drug Profile

Aleniglipron - Gasherbrum Bio

Alternative Names: GSBR-1290

Latest Information Update: 25 Jun 2026

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At a glance

  • Originator Gasherbrum Bio
  • Developer Gasherbrum Bio; Structure Therapeutics
  • Class Antihyperglycaemics; Antiparkinsonians; Obesity therapies; Small molecules
  • Mechanism of Action Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Obesity; Type 2 diabetes mellitus
  • Preclinical Parkinson's disease

Most Recent Events

  • 22 Jun 2026 Gasherbrum Bio plans a phase III ACCOMPLISH-1 trial for Obesity in USA (PO) in July 2026 (NCT07654361)
  • 08 Jun 2026 Updated adverse events and efficacy data from a phase II ACCESS trial in Obesity released by Structure Therapeutics
  • 16 Mar 2026 Structure Therapeutics anticipates a Type B End-of-Phase 2 meeting with US FDA, in the second quarter of 2026

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