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PRT 3645

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Drug Profile

PRT 3645

Alternative Names: CDK4/6 Inhibitor; PRT-3645

Latest Information Update: 26 Jul 2024

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At a glance

  • Originator Prelude Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 26 Jun 2024 Prelude Therapeutics completes the phase I trial in Solid tumors (Late-stage disease, Metastatic disease, Recurrent) in USA and Singapore (PO) (NCT05538572)
  • 09 Apr 2024 Pharmacodynamics data from the preclinical studies in Breast cancer, Non-small cell lung cancer and Colorectal cancer released by Prelude Therapeutics
  • 05 Apr 2024 Pharmacodynamics data form preclinical trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research

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