EGFR806-specific chimeric antigen receptor CAR-T cell therapy - Cellevolve/ Seattle Childrens Therapeutics
Alternative Names: EGFR806-CAR-T cell therapy - Cellevolve/ Seattle Childrens TherapeuticsLatest Information Update: 28 Dec 2022
At a glance
- Originator Seattle Childrens Therapeutics
- Developer Seattle Children's Hospital
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II CNS cancer
Most Recent Events
- 08 Dec 2022 Phase-I/II clinical trials in CNS cancer (In adolescents, In children, In infants, Recurrent, Second-line therapy or greater, In adults) in USA (Intratumoural)
- 08 Dec 2022 Phase-I/II clinical trials in CNS cancer (In adolescents, In children, In infants, Recurrent, Second-line therapy or greater, In adults) in USA (IV)
- 09 Mar 2022 EGFR806-specific chimeric antigen receptor T cell therapy licensed to Cellevolve worldwide for CNS cancers