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QLS 31905

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Drug Profile

QLS 31905

Alternative Names: anti-claudin 18.2/CD3 bispecific antibody; QLS-31905

Latest Information Update: 11 Sep 2025

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At a glance

  • Originator Qilu Pharmaceutical
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 03 Sep 2025 Qilu Pharmaceutical plans a phase-II trial for Biliary cancer (Inoperable/Unresectable, First-line therapy, Combination therapy, Late-stage disease, Metastatic disease) in September 2025 (Parenteral), (NCT07151872)
  • 28 Jul 2025 Qilu Pharmaceutical plans a phase III trial for Pancreatic cancer (Combination therapy, Late-stage disease, First-line therapy) (IV, Infusion), in September 2025 (NCT07079228)
  • 30 May 2025 Efficacy and adverse events data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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