Drug Profile

KM 254-ADC

Alternative Names: KM-254-ADC

Latest Information Update: 28 Apr 2026

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At a glance

Originator Combio Pharmaceutical
Developer Xuanzhu Biopharmaceutical
Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Apr 2026 No recent reports of development identified for preclinical development in Solid-tumours in China
25 Mar 2022 Preclinical trials in Solid tumours in China (unspecified route) before March 2022 (Xuanzhu Biopharmaceutical pipeline, March 2022)
03 Feb 2021 Xuanzhu Biopharmaceutical acquires Combio Pharmaceutical

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