Drug Profile

ABBV 8736

Alternative Names: ABBV-8736; CEL-383

Latest Information Update: 23 Feb 2026

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At a glance

Originator Celsius Therapeutics
Developer AbbVie
Class Anti-inflammatories; Antibodies
Mechanism of Action Triggering receptor expressed on myeloid cells-1 antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

17 Feb 2026 AbbVie plans a phase I trial (In volunteers) in USA in February 2026 (IV) (NCT07413133)
11 Feb 2026 AbbVie initiates a phase I trial (In volunteers) in the US (IV) (SC) (NCT07413133) _
09 Feb 2026 AbbVie plans a phase I pharmacokinetics, bioavailability, immunogenicity, safety, and tolerability trial in Healthy subjects in the US (NCT07413133)

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