Drug Profile

JAB 23E73

Alternative Names: JAB-23E73

Latest Information Update: 19 Mar 2026

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At a glance

Originator Jacobio Pharmaceuticals
Class Antineoplastics; Small molecules
Mechanism of Action KRAS protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

10 Mar 2026 Updated adverse events and efficacy data from a phase-I/II trial in Solid tumours released by Jacobio Pharmaceuticals
10 Mar 2026 Jacobio Pharmaceuticals plans a phase-I/III trial for Adenocarcinoma (First-line therapy, Combination therapy) in China (PO),
01 Feb 2026 China's NMPA approves IND application for phase-I/III in Adenocarcinoma (First-line therapy, Combination therapy)

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