Drug Profile

JAB 23E73

Alternative Names: JAB-23E73

Latest Information Update: 05 Jan 2026

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At a glance

Originator Jacobio Pharmaceuticals
Class Antineoplastics; Small molecules
Mechanism of Action KRAS protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

25 Dec 2025 Jacobio Pharma and AstraZeneca agree to co-develop JAB-23E73 for Solid tumours
23 Oct 2025 Phase-I clinical trials in Solid tumours (Late-stage disease) in USA (PO) before October 2025
23 Oct 2025 Pharmacokinetics and pharmacodynamics data from a preclinical trials in Solid tumours released by Jacobio Pharmaceuticals

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