Drug Profile

LAVA 1266

Alternative Names: LAVA-1266

Latest Information Update: 28 Aug 2025

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At a glance

Originator Lava Therapeutics
Class Antineoplastics; Bispecific antibodies; Immunotherapies
Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

13 Aug 2025 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in Australia (IV)
13 Aug 2025 Discontinued - Phase-I for Myelodysplastic syndromes (Second-line therapy or greater) in Australia (IV)
10 Jan 2025 Pharmacodynamics data from preclinical studies in Acute myeloid leukaemia released by LAVA Therapeutics

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