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LYL 331

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Drug Profile

LYL 331

Alternative Names: LYL-331

Latest Information Update: 28 Apr 2026

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At a glance

  • Originator Lyell Immunopharma
  • Class Antineoplastics; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Synovial sarcoma
  • No development reported Solid tumours

Most Recent Events

  • 28 Apr 2026 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
  • 17 Oct 2022 Preclinical trials in Synovial sarcoma in USA (Parenteral) (Lyell Immunopharma pipeline, October 2022)
  • 29 Mar 2022 Lyell Immunopharma plans to file IND application for LYL 331 in Solid tumours in late 2022 or early 2023

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