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CM 336

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Drug Profile

CM 336

Alternative Names: BCMA/CD3 bispecific antibody; CM-336; OM-336

Latest Information Update: 23 Sep 2025

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At a glance

  • Originator KeyMed Biosciences
  • Developer KeyMed Biosciences; Ouro Medicines
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Autoimmune haemolytic anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyloidosis
  • Phase I/II Bullous pemphigoid; Multiple myeloma
  • Phase I Idiopathic thrombocytopenic purpura
  • Clinical Phase Unknown Autoimmune haemolytic anaemia

Most Recent Events

  • 18 Sep 2025 Keymed Biosciences plans a phase III trial for Multiple myeloma (Second-line therapy or greater) in the China (SC, injection) in September 2025 (NCT07181239)
  • 16 Sep 2025 Keymed Biosciences plans a phase I/II trial for Autoimmune cytopenia (Treatment-experienced) in China (SC, Injection) in October 2025 (NCT07175493)
  • 27 Aug 2025 Institute of Hematology & Blood Diseases Hospital, China plans to initiate a phase II trial for Systemic Light Chain Amyloidosis (Newly diagnosed) in China (SC) (NCT07151690)

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