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MTX 652

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Drug Profile

MTX 652

Alternative Names: DMX-652; MTX-652

Latest Information Update: 23 Jul 2026

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At a glance

  • Originator MISSION Therapeutics
  • Class Antifibrotics; Heart failure therapies; Small molecules; Urologics
  • Mechanism of Action Usp30 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Acute kidney injury; Heart failure; Idiopathic pulmonary fibrosis; Muscular dystrophies; Renal failure

Most Recent Events

  • 23 Jul 2026 MTX 652 is still in phase-I development in Acute kidney injury(In volunteers) in United Kingdom (PO)
  • 17 Jul 2026 Mission Therapeutics acquire MTX 652 from Dimerix Biosciences
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Acute kidney injury(In volunteers) in United Kingdom (PO)

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